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This Week in Evolution

This Week in Evolution is a podcast on the biology behind what makes us tick.
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Now displaying: 2023
May 12, 2023

Nels and Vincent provide insights into the mystery of mouse mummies on the summits of >6000 m Andean volcanoes, including whether they were living there and if so why?

Hosts: Nels Elde and Vincent Racaniello

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•Join the MicrobeTV Discord server
•Mystery of mouse mummies (bioRxiv)

Science Picks

NelsZoonomia
VincentSeaPhages

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

Apr 25, 2023

Nels and Vincent discuss the observation that cells on a boundary of a solid tumor have higher growth rates compared to those in the center and how to model this difference using genome sequencing data.

Hosts: Nels Elde and Vincent Racaniello

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•Evolutionary models of solid tumor growth (Nat Ecol Evol)

Science Picks

NelsTWiV 1000
Vincent The dream of wiping out polio might need a rethink

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Mar 26, 2023

Nels and Vincent review a study of the dogs of Chernobyl which reveals that genetically distinct populations with different amounts of western breed contributions to their genomes, the first step in assessing the effects of exposure to long-term ionizing radiation.

Hosts: Nels Elde and Vincent Racaniello

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The dogs of Chernobyl (Science Adv)
•What the dogs of Chernobyl can teach us (Stat)
Letters read on TWiEVO 88

Science Picks

Nels – Hellbent documentary and Insufficient evidence for natural selection associated with the Black Death
Vincent – BioRender

Listener Pick

Walter – Oded Rechavi and interview

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

Feb 21, 2023

Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness.

Hosts: Nels Elde and Vincent Racaniello

Guest: Nathan Clark

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•Join the MicrobeTV Discord server
•Gene loss in marine mammals (TWiEVO 34)
•Gene change underlying mammalian hair loss (eLife)
Letters read on TWiEVO 87

Science Picks

Nels – Local news coverage of Amanda, Maria, and Nathan’s paper
Vincent – Discovering Retroviruses by Anna Marie Skalka
Nathan – Genomics of Secondarily Temperate Adaptation in the Only Non-Antarctic Icefish

Music on TWiEVO is performed by Trampled by Turtles

Send your evolution questions and comments to twievo@microbe.tv

Feb 5, 2023

Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop.

Hosts: Nels Elde and Vincent Racaniello

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•Join the MicrobeTV Discord server
•Novel stop codon reassignment mechanisms (Nature)

Science Picks

NelsProtein Synthesis: An epic on the cellular level 

VincentWidespread stop-codon recoding in bacteriophages may regulate translation of lytic genes discussed on TWiM 277

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Send your evolution questions and comments to twievo@microbe.tv

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