Nathan joins Nels and Vincent to discuss his approach to understanding how species adopt novel traits to overcome challenges, and its application to identifying coding and noncoding sequence changes that underlie mammalian hairlessness.
Hosts: Nels Elde and Vincent Racaniello
Guest: Nathan Clark
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•Gene loss in marine mammals (TWiEVO 34)
•Gene change underlying mammalian hair loss (eLife)
•Letters read on TWiEVO 87
Nels – Local news coverage of Amanda, Maria, and Nathan’s paper
Vincent – Discovering Retroviruses by Anna Marie Skalka
Nathan – Genomics of Secondarily Temperate Adaptation in the Only Non-Antarctic Icefish
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Nels and Vincent discuss how evolution of changes in stop codon assignment might occur, and a novel mechanism for altering the meaning of translation stop codons discovered in a trypanosomatid with the apropos name, Blastocrithidia nonstop.
Hosts: Nels Elde and Vincent Racaniello
Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email
Become a patron of TWiEVO
•Join the MicrobeTV Discord server
•Novel stop codon reassignment mechanisms (Nature)
Nels – Protein Synthesis: An epic on the cellular level
Vincent – Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes discussed on TWiM 277
Music on TWiEVO is performed by Trampled by Turtles
Send your evolution questions and comments to twievo@microbe.tv